By Jacques Descotes
This article offers a concise and entire creation to key immunotoxicological matters for all these attracted to, yet without previous wisdom of, this zone of toxicology. the 1st part explores the overall healthiness effects of immunotoxicity, particularly the antagonistic results with regards to chemically-induced immunosuppression and immunostimulation, allergic reaction reactions and autoimmune illnesses, with an summary of significant immunotoxicants. the second one half describes the newest equipment used to notice and overview, preclinically and clinically, the unforeseen immunotoxic results of xenobiotics. tendencies in imposing suggestions and up to date alterations to the regulatory features also are thought of. The 3rd part examines attainable destiny advancements, together with In Vitro equipment, biomarkers of immunotixicity and chance review.
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Additional resources for An introduction to immunotoxicology
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Several cytokines have neurotransmitter activity and their possible role in psychiatric diseases is an area of growing research. , 1994). The impact of the immune system on other physiological functions is still poorly recognised, although it may account for adverse effects caused by immunomodulating compounds. Conclusion This brief overview of the immune system shows how complex and intricated immune responses can be, due to the interplay of many redundant or conflicting mechanisms. In addition, other biological systems, such as the second messengers or the complement pathway, are involved.
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